Castration With Abiraterone 250 mg Without LHRH Analogs or Blockers in Patients With Prostate Cancer Requiring Hormonal Intensification (Multicenter Phase 2)

Phase 2 Recruiting 60 enrolled SMED Clinical Research

NaSingle-groupOpen-labelTreatment

Summary

Hypothesis The use of Abiraterone 250 mg with food + prednisone, without LHRH analogs or blockers (ADT), achieves castration-level testosterone at 30 days in ≥80-90% of cases.

Timeline

Start: 2025-12-01
Primary completion: 2026-12-31
Completion: 2027-03-30

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Abiraterone acetate	Small molecule	250 mg	—
Background	Prednisone	Other / unclassified	5 mg	—

Indications

No indication recorded.