drugset / Trial / NCT07300488

Efficacy and Safety of Pracytarabine Versus Regorafenib in the Treatment of Patients With Hepatocellular Carcinoma

NCT07300488

Phase 2/3 Active not recruiting 60 enrolled Xi'an Xintong Pharmaceutical Research Co.,Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a Phase 2/3 study evaluating the efficacy and safety of Pracytarabine versus regorafenib in patients with advanced hepatocellular carcinoma (HCC) who have experienced treatment failure with standard systemic therapies involving targeted drugs and immune checkpoint inhibitors, or dual immune checkpoint inhibitors.

Timeline

Start
2025-09-01
Primary completion
2027-02-28
Completion
2027-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Pracytarabine Unknown 1200 mg/m2 Intravenous
Comparator Regorafenib Small molecule 160 mg