drugset / Trial / NCT07300488
Efficacy and Safety of Pracytarabine Versus Regorafenib in the Treatment of Patients With Hepatocellular Carcinoma
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a Phase 2/3 study evaluating the efficacy and safety of Pracytarabine versus regorafenib in patients with advanced hepatocellular carcinoma (HCC) who have experienced treatment failure with standard systemic therapies involving targeted drugs and immune checkpoint inhibitors, or dual immune checkpoint inhibitors.
Timeline
- Start
- 2025-09-01
- Primary completion
- 2027-02-28
- Completion
- 2027-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pracytarabine | Unknown | 1200 mg/m2 | Intravenous |
| Comparator | Regorafenib | Small molecule | 160 mg | — |