Efficacy and Safety of Minocycline in the Treatment of Intracerebral Hemorrhage

Summary

This study plans to enroll 1248 patients with supratentorial ICH within 24 hours of onset across multiple stroke centers. After randomization, the control group will only receive medical therapy. The experimental group, after randomization, will receive an initial dose of 200 mg of minocycline hydrochloride capsules in addition to medical ttherapy, followed by 100 mg orally every 12 hours for 7 days, resulting in a total of 14 administrations. Both groups will be followed for 180 days to evaluate the efficacy and safety of minocycline in the treatment of ICH.

Timeline

Start

2025-12-31

Primary completion

2028-12-31

Completion

2028-12-31

Drugs

Indications