drugset / Trial / NCT07305935
Comparison of Early Caffeine Administration Vs Supportive Therapy in Preventing Acute Kidney Injury
RandomizedParallel-groupOpen-labelPrevention
Summary
Recent observational data point towards a reduced incidence of acute kidney injury (AKI) with early caffeine use, but high-quality randomized controlled trials comparing early caffeine initiation to supportive therapy alone are lacking. This study aims to fill this critical gap by comparing the efficacy of early caffeine administration versus supportive therapy in preventing AKI in preterm neonates.
Timeline
- Start
- 2025-10-01
- Primary completion
- 2026-03-31
- Completion
- 2026-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Caffeine | Small molecule | 5 mg/kg | Intravenous |
Indications
No indication recorded.