drugset / Trial / NCT07306286

Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

NCT07306286 ↗

Phase 2 Recruiting 20 enrolled Ruijin Hospital
NaSingle-groupOpen-labelTreatment

Summary

The study explores the efficacy and safety of cryoablation combined with the dual-function antibody PD-1/CTLA-4 (Apalulizumab) for the treatment of locally advanced pancreatic cancer following failure of first-line AG therapy. This research aims to accumulate more clinical evidence and treatment options for second-line therapy in locally advanced pancreatic cancer following failure of first-line regimen.

Timeline

Start
2025-12-15
Primary completion
2027-08-01
Completion
2027-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Apalulizumab Unknown — Intravenous