Intramuscular vs Rectal Progesterone in Preventing Preterm Labour After Cervical Cerclage

Summary

Preterm labour is a major cause of neonatal morbidity and mortality worldwide. Progesterone supplementation is known to help reduce the risk of preterm birth in high-risk women. This randomized controlled trial compared the effectiveness of intramuscular progesterone and rectal progesterone in preventing preterm labour among pregnant women who had undergone cervical cerclage. The study aimed to determine which route of progesterone administration provides better pregnancy prolongation and improved neonatal outcomes.

Timeline

Start

2021-10-26

Primary completion

2022-04-25

Completion

2022-04-25

Drugs

Indications