drugset / Trial / NCT07310797
Comparison of Mirabegron and Tamsulosin for Ureteral Stone Expulsion
RandomizedParallel-groupOpen-labelTreatment
Summary
This randomized controlled trial compares the efficacy and safety of four treatment strategies for ureteral stone expulsion: Mirabegron alone, Tamsulosin alone, a combination of both, and standard conservative care. Participants diagnosed with ureteral stones will be randomly assigned to one of these four groups. The primary objective is to evaluate the stone expulsion rate within 4 weeks. The study also assesses time to expulsion, pain intensity, analgesic use, and potential side effects.
Timeline
- Start
- 2026-02-13
- Primary completion
- 2029-12-31
- Completion
- 2030-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mirabegron | Other / unclassified | 50 mg | Oral |
| Subject | Tamsulosin | Other / unclassified | 0.4 mg | Oral |