drugset / Trial / NCT07313917

A Study to Evaluate the Efficacy and Safety of LP-003 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

NCT07313917

Phase 2 Not yet recruiting 150 enrolled Longbio Pharma
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group Phase II clinical trial. Its primary objective is to explore and preliminarily evaluate the efficacy and safety of LP-003 Injection in the treatment of participants with chronic rhinosinusitis with nasal polyps (CRSwNP), as well as to investigate its pharmacokinetic (PK), pharmacodynamic (PD) profiles, and immunogenicity.

Timeline

Start
2026-01-20
Primary completion
2027-02-28
Completion
2027-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject LP-003 Unknown 300 mg Subcutaneous
Subject LP-003 Unknown 450 mg Subcutaneous