Meropenem vs Azithromycin Efficacy in Case XDR Enteric Fever

Summary

1. Primary Objective: o To evaluate the efficacy of intravenous azithromycin compared with meropenem in the treatment of extensively drug-resistant (XDR) enteric fever. 2. Secondary Objectives: * To evaluate the fever defervescence and Salmonella Typhi eradication * To evaluate the cost-effectiveness of intravenous azithromycin versus meropenem in treating XDR enteric fever. 3. Exploratory Objectives: * To evaluate the drug resistance against intravenous azithromycin versus in treating XDR enteric fever.

Timeline

Start

2025-04-22

Primary completion

2027-01-15

Completion

2027-01-15

Drugs

Indications