drugset / Trial / NCT07319208

Efficacy of Early Continuous Infusion of HSS on the Neurological Outcome at 6 Months in TBI Patients.

NCT07319208 ↗

Phase 3 Recruiting 760 enrolled Nantes University Hospital
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to demonstrate the efficacy of early continuous intravenous infusion of hypertonic saline solution (HSS) to improve survival and independence in daily life activities (at 6 months) of patients with traumatic brain injury at high risk of intracranial hypertension.

Timeline

Start
2026-04-21
Primary completion
2028-06-01
Completion
2029-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Hypertonic saline solution Unknown 20 % Intravenous