drugset / Trial / NCT07319871

A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

NCT07319871

Phase 1 Recruiting 40 enrolled Janssen Research & Development, LLC
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to identify the recommended phase 2 combination dose (RP2CD) of Pasritamig in combination with JNJ-86974680 in Part 1 (Dose finding) of the study and to determine how safe and tolerable the RP2CD is for treatment of participants with advanced prostate cancer in Part 2 (Dose expansion) of study.

Timeline

Start
2026-01-14
Primary completion
2027-01-07
Completion
2027-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject JNJ-86974680 Unknown Oral
Subject Pasritamig Other / unclassified Intravenous

Indications