Comparative Effects of CGF and PRP in Impacted Third Molar Surgery

Summary

This study evaluates the effects of two different blood products obtained from the patient's own blood (Concentrated Growth Factor \[CGF\] and Platelet-Rich Plasma \[PRP\]) on healing after wisdom tooth extraction. The aim is to determine whether applying these materials to the extraction area reduces postoperative pain, facial swelling, and the risk of dry socket compared to standard healing.

Timeline

Start

2024-05-02

Primary completion

2025-05-02

Completion

2025-05-02

Publications

• Valiyev E, Dogan A. Effects of concentrated growth factor and platelet-rich plasma on postoperative pain and edema following impacted mandibular third molar surgery: a randomized controlled clinical trial. BMC Oral Health. 2026 Jun 29. doi: 10.1186/s12903-026-09054-3. Online ahead of print.

Drugs

Indications