drugset / Trial / NCT07328581

BCMA-CD19 cCAR T for the Treatment of Refractory Lupus

NCT07328581 ↗

Phase 1/2 Not yet recruiting 20 enrolled iCell Gene Therapeutics
NaSequentialOpen-labelTreatment

Summary

This is a Phase I, IIa, Single-Arm, interventional, open label, treatment study to evaluate the safety and tolerability of BCMA-CD19-IL-15/IL15sushi cCAR T cells in patients with relapsed and/or refractory SLE, with or without Lupus Nephritis.

Timeline

Start
2026-01
Primary completion
2028-12
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject ICG318 Cell therapy — —