drugset / Trial / NCT07337434
To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital
RandomizedParallel-groupOpen-labelTreatment
Summary
This study aims to compare efficacy of methotrexate vs apremilast in the management of chronic plaque psoriasis.Given the high prevalence of psoriasis in Pakistan and the significant psychological impact on patients, particularly in Peshawer,this study will provide valuable insights into optimal treatment strategies.
Timeline
- Start
- 2025-12-25
- Primary completion
- 2026-06-25
- Completion
- 2026-06-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Apremilast | Small molecule | 30 mg | Oral |
| Subject | Methotrexate | Small molecule | 10 mg | — |
| Subject | Methotrexate | Small molecule | 25 mg | — |