drugset / Trial / NCT07341360

Pseudovax - A Cancer Vaccine for Patients With Pseudomyxoma Peritonei

NCT07341360

Phase 0 Recruiting 10 enrolled Oslo University Hospital BeiGene · collab
NaSingle-groupOpen-labelTreatment

Summary

Participants will receive vaccination with Pseudovax/GM-CSF in combination with PD-1 inhibitor tislelizumab over a period of up to two years. The vaccine is expected to reactivate measurable immune response, and tislelizumab to restore anticancer immunity in patients with GNAS mutated pseudomyxoma peritonei.

Timeline

Start
2025-10-13
Primary completion
2029-12-31
Completion
2034-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject 100 mg of humanized IgG4 mAb in 10 mL of isotonic solution Monoclonal antibody 100 mg
Background Molgramostim Protein / enzyme biologic 100 ug