drugset / Trial / NCT07341672
A Single-center, Randomized, Open-label, Parallel-design Clinical Study to Evaluate the Pharmacokinetic Effects of Itraconazole, Fluconazole or Efavirenz on a Single Dose of Clifutinib in Healthy Participants
RandomizedParallel-groupOpen-labelTreatment
Summary
Evaluate the pharmacokinetic effects of itraconazole, fluconazole, or efavirenz on a single - dose of Clifutinib and the safety of the combination therapy in healthy participants.
Timeline
- Start
- 2026-12-31
- Primary completion
- 2027-04-23
- Completion
- 2027-05-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clifutinib | Unknown | 40 mg | — |
| Comparator | Efavirenz | Other / unclassified | 600 mg | — |
| Comparator | Fluconazole | Small molecule | 400 mg | — |
| Comparator | Itraconazole | Small molecule | 200 mg | Oral |
Indications
No indication recorded.