Comparing of Sesame Oil, Nitroglycerin Ointment, and Aloe Vera Gel

Summary

compare the effectiveness sesame oil, aloe Vera gel, and nitroglycerin ointment prevention of phlebitis.

Timeline

Start

2026-05-11

Primary completion

2026-06-20

Completion

2026-07-20

Publications

• Results Shakhbazova A, Marsch AF. Systemic 5-fluorouracil induced lupus erythematosus: a review of the literature. Dermatol Online J. 2019 Nov 15;25(11):13030/qt3nw0p7hn.
• Results Yousef MI, Saad AA, El-Shennawy LK. Protective effect of grape seed proanthocyanidin extract against oxidative stress induced by cisplatin in rats. Food Chem Toxicol. 2009 Jun;47(6):1176-1183. doi: 10.1016/j.fct.2009.02.007.
• Results Kadoyama K, Miki I, Tamura T, Brown JB, Sakaeda T, Okuno Y. Adverse event profiles of 5-fluorouracil and capecitabine: data mining of the public version of the FDA Adverse Event Reporting System, AERS, and reproducibility of clinical observations. Int J Med Sci. 2012;9(1):33-9. doi: 10.7150/ijms.9.33. Epub 2011 Nov 17.
• Results Tsimberidou AM, Braiteh F, Stewart DJ, Kurzrock R. Ultimate fate of oncology drugs approved by the us food and drug administration without a randomized Trial. J Clin Oncol. 2009 Dec 20;27(36):6243-50. doi: 10.1200/JCO.2009.23.6018. Epub 2009 Oct 13.
• Results Sudhakar S, Jacob A, Hegde NN, Chaudhary RK, Mateti UV, Shetty V. Evaluation of chemotherapy infusion and phlebitis among cancer patients: A prospective observational single-center study. J Oncol Pharm Pract. 2023 Dec;29(8):1944-1950. doi: 10.1177/10781552231161517. Epub 2023 Mar 5.
• Results Outcomes of Patients with Chronic Lymphocytic Leukemia Treated with Chemotherapy in Middle Euphrates Region of Iraq: Data from Developing CountryMjali A. 2020;12
• Results Johnson CM, Wei C, Ensor JE, Smolenski DJ, Amos CI, Levin B, Berry DA. Meta-analyses of colorectal cancer risk factors. Cancer Causes Control. 2013 Jun;24(6):1207-22. doi: 10.1007/s10552-013-0201-5. Epub 2013 Apr 6.
• Results Some Facts About Cancers in Karbala province of Iraq, 2012-2020Mjali A, Baroodi B. Asian Pacific Journal of Cancer Care.2020;5.
• Results Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov;68(6):394-424. doi: 10.3322/caac.21492. Epub 2018 Sep 12.
• Results Argiles G, Tabernero J, Labianca R, Hochhauser D, Salazar R, Iveson T, Laurent-Puig P, Quirke P, Yoshino T, Taieb J, Martinelli E, Arnold D; ESMO Guidelines Committee. Electronic address: [email protected]. Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2020 Oct;31(10):1291-1305. doi: 10.1016/j.annonc.2020.06.022. Epub 2020 Jul 20. No abstract available.
• Results Iraqi Cancer Board: Results of the Iraqi Cancer Registry 2011. Baghdad, Iraqi Cancer Registry Center: Ministry of Health, 2013.
• Results Alwan NA. Breast cancer: demographic characteristics and clinico-pathological presentation of patients in Iraq. East Mediterr Health J. 2010 Nov;16(11):1159-64.
• Results International Agency for Cancer Research (IARC); World health Organization: GLOBOCAN 2012 v1.1, Cancer Incidence and Mortality Worldwide: IARC Cancer Base, 2012, No. 11 [Online], Available from: http://globocan.iarc.fr , accessed on 16/05/2016.
• Results American Cancer society (A): Breast cancer:Facts and Figures 2015-2016. Atlanta:Author, 2016, [Online], Available from: www.cancer.org/cancerfactsstatistics/acspc-046381 , accessed on 26/01/2016.
• Results Akbari H, Raufi S, Hekmat po D , Anbari K (2014). Comparaing the effect of Nitroglycerin and Clobetazol Ointments on Prevention of Superficial Intravenous Catheter Induced Phlebitis. Evide Based Care, 4, 71-80
• Results Annai S, Deepa R. Effectiveness of aloe vera gel application on phlebitis. Nurse Care Open Acces J. 2023;9(3):122-128. DOI: 10.15406/ncoaj.2023.09.00271
• Results Mohammadyan S, Seidi J, Nouri B, Fathi M. [A Comparative Study on the Effect of Aloe Vera and Nitroglycerin Ointment on the Incidence and Severity of Phlebitis Caused by the Peripheral Catheter]. Sci J Kurdistan Univ Med Sci. 2020;25(2):44-53. Persian
• Results Ghazanfari Z, Foroghamari G, Mirhosseini M. [The nursing staff view about barriers of using pain relief methods]. Crit Care Nurs. 2011;3(4):153-6. Persian
• Results Dorchin M, Dorchin A, Attar N, Moradi N, Sharifzadeh Z (2021) The Role of Rubbing Sesame Oil in Improving Chemotherapy Induced Phlebitis in Cancer Patients at Raha Cancer Clinic: Dezful. J Pharma Care Health Sys. 8:234.
• Results Behnamfar N, Parsa Yekta Z, Mojab F, Kazem Naeini SM. The effect of nigella sativa oil on the prevention of phlebitis induced by chemotherapy: a clinical trial. Biomedicine (Taipei). 2019 Sep;9(3):20. doi: 10.1051/bmdcn/2019090320. Epub 2019 Aug 27.
• Results Shafipour SZ, Mosayebi N, Asgari F, Atrkarroushan Z , Pasdaran A (2017). Effect of External Use of Sesame Oil in the Prevention of Chemotherapy-Induced Phlebitis in Children
• Results Gonzalez Lopez JL, Arribi Vilela A, Fernandez del Palacio E, Olivares Corral J, Benedicto Marti C, Herrera Portal P. Indwell times, complications and costs of open vs closed safety peripheral intravenous catheters: a randomized study. J Hosp Infect. 2014 Feb;86(2):117-26. doi: 10.1016/j.jhin.2013.10.008. Epub 2013 Dec 1.
• Results Y. Gao, T. Jiang, S. Mei, S. Zhang, C. Zhu, Y. Sun. Meta-analysis of Aloe vera for the prevention and treatment of chemotherapy-induced phlebitis. Int J Clin Exp Med. 9(6); 2016: 9642- 50
• Results Kaewwilai, S., & Uadrang, S. (2022). อุบัติ การณ์ การ เกิด หลอดเลือด ด า อักเสบ อุด ตัน ใน ผู้ ป่ วย มะเร็ง ที่ ได้ รับ ยา เคมี บ าบัด. Journal of The Department of Medical Services, 47(3), 27-31
• Results Ahmed, K. A., & Hamawandi, N. M. Assessment of peripheral intravenous cannula insertion pr actice among health care workers of sulaimani surgical teaching hospital, sulaimani, iraq
• Results Gonzalez T. Chemotherapy extravasations: prevention, identification, management, and documentation. Clin J Oncol Nurs. 2013 Feb;17(1):61-6. doi: 10.1188/13.CJON.61-66.
• Results Patrick, C. N. (2010). Diagnosis and Treatment, 82(2). https://doi.org/10.1016/S0195- 5616(00)06007-1.
• Results Hayder, A. J., & Mohammed, S. J. (2018). Effectiveness of an Education Program on Nurses' Knowledge Concerning Side Effect of Chemotherapy in Baghdad Teaching Hospitals. Indian Journal of Public Health Research & Development, 9(8).
• Results Harris V, Hughes M, Roberts R, Dolan G, Williams EM. The Development and Testing of a Chemotherapy-Induced Phlebitis Severity (CIPS) Scale for Patients Receiving Anthracycline Chemotherapy for Breast Cancer. J Clin Med. 2020 Mar 5;9(3):701. doi: 10.3390/jcm9030701.
• Results National Cancer Control Plan of Egypt, (2020). http:// ahfonline. net/ files/ mp/ Cancer %20Control %20Plan.pdf
• Results MO) Ministry of Health. (2013). Iraqi Cancer Registry Center, Baghdad
• Results Mimoz O, Villeminey S, Ragot S, Dahyot-Fizelier C, Laksiri L, Petitpas F, Debaene B. Chlorhexidine-based antiseptic solution vs alcohol-based povidone-iodine for central venous catheter care. Arch Intern Med. 2007 Oct 22;167(19):2066-72. doi: 10.1001/archinte.167.19.2066.
• Results Ali HD. Quality of life and its related factors in cancer patients undergoing chemotherapy. J Kerm University Med Sci. 2006; 1(2): 119-110.
• Results Otto SE. Oncology Nursing. Ed. 4th ed Mosby, Toronto. Harcourt Health Sciences CO. 2001
• Results Shojaei Tehrani Hossein. Textbook of Medicine, Prevention and Social. Chronic NonCommunicable Diseases and Common Infectious Diseases. Med Sci Tehran. 2003;4(1): 28-25.
• Results El-Sayad, H. E., Aboalizm, S. E., & Abd Elhy, A. H. (2023). Effect of preventive measures on chemotherapy induced phlebitis among patients with cancer. Menoufia Nursing Journal, 8(1), 187-202.
• Results Hussin, B. K. (2021 Prevention of Extravasation Non-Cytotoxic Agents (Review Study). Himalayan Journal of Nursing and Midwifery, 1(5).
• Results Carr PJ, Glynn RW, Dineen B, Kropmans TJ. A pilot intravenous cannulation team: an Irish perspective. Br J Nurs. 2010 May 27-Jun 9;19(10):S19-27. doi: 10.12968/bjon.2010.19.Sup3.48214.
• Results Carr PJ, Glynn RW, Dineen B, Devitt D, Flaherty G, Kropmans TJ, Kerin M. Interns' attitudes to IV cannulation: a KAP study. Br J Nurs. 2011 Feb 24-Mar 9;20(4):S15-20. doi: 10.12968/bjon.2011.20.4.S15.

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