drugset / Trial / NCT07346690

A Study Testing the Effects of Different THC Doses on Psychological and Biological Function

NCT07346690

Phase 1 Not yet recruiting 24 enrolled University of Calgary
RandomizedCrossoverQuadruple-blindBasic science

Summary

The goal of this clinical trial is to learn how a investigational medicinal product (THC) affects psychological and physical responses in healthy adults with prior cannabis use experience. The main questions it aims to answer are: \- How do different dose levels of the investigational medicinal product (THC) influence short-term subjective and physiological responses? Researchers will compare three dose levels of the study drug to a placebo (a look-alike substance with no active ingredient) to see how responses vary across sessions. Participants will: * Attend four in-person study visits, each involving a single dose of either the study drug or placebo * Complete questionnaires about their moment-to-moment experiences * Have their heart rate, blood pressure, and other physical measures monitored * Undergo serial blood sampling to measure circulating biomarkers

Timeline

Start
2026-02-01
Primary completion
2028-02-01
Completion
2028-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Δ9-THC Unknown 6 mg Oral
Subject Δ9-THC Unknown 9 mg Oral
Subject Δ9-THC Unknown 15 mg Oral

Indications

No indication recorded.