drugset / Trial / NCT07347405

Psilocybin Whole Mushroom for the Treatment of Obsessive-compulsive Disorder.

NCT07347405

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The study tries to improve our treatments for people who have obsessive-compulsive disorder (OCD) by testing psilocybin, a mind altering drug that changes activity in brain areas involved in OCD. 30 patients with moderate or more severe OCD who are not taking mind altering medications or street drugs will participate in a 12 week study. Participants will be assigned (by luck of the draw) to take a low, medium, or high dose whole psilocybin mushroom contained in three chocolate pieces, prepared for this study by the Scottsdale Research Institute.

Timeline

Start
2026-05-18
Primary completion
2028-01
Completion
2029-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Psilocybin Other / unclassified 10 mg Oral
Subject Psilocybin Other / unclassified 20 mg Oral
Subject Psilocybin Other / unclassified 30 mg Oral