CAR-T Therapy Targeting CD19 and BCMA in Highly Sensitized Kidney Transplant Participants

Summary

The purpose of this study is to assess the safety, tolerability, and efficacy of AZD0120 in highly sensitized adult participants with ESKD awaiting kidney transplant-who, as assessed by investigators, are improbable desensitization through conventional treatments (e.g., plasmapheresis and immunoadsorption)- with or without living donors.

Timeline

Start

2026-01-28

Primary completion

2026-12-31

Completion

2029-12-31

Drugs

Indications