drugset / Trial / NCT07354659

Immunogenicity and Safety of SYS6017 in the Participants Aged 40 Years and Above

NCT07354659

Phase 2 Not yet recruiting 800 enrolled CSPC Megalith Biopharmaceutical Co.,Ltd.
RandomizedParallel-groupTriple-blindPrevention

Summary

Herpes zoster is caused by the reactivation of latent varicella-zoster virus (VZV) which stays in latency after its primary infection. Immunosenescence contributes significantly to elevating morbidity associated with aging. Vaccination plays a key role in reducing the disease burden of zoster and the associated complications. We are conducting a study entitled "A Randomized, Blinded, Placebo- and Active-Controlled, Adaptive Phase 2 Clinical Trial to Evaluate the Immunogenicity and Safety of SYS6017 (a Herpes Zoster mRNA Vaccine) in Healthy Participants Aged 40 Years and Above".

Timeline

Start
2026-01-10
Primary completion
2027-03-10
Completion
2027-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject SYS6017 Messenger RNA (mRNA)
Comparator VARICELLA ZOSTER VIRUS ENVELOPE GLYCOPROTEIN E Vaccine

Indications