drugset / Trial / NCT07358546

A Study of Efimosfermin Alfa in Adults With Hepatic Impairment

NCT07358546 ↗

Phase 1 Recruiting 32 enrolled GlaxoSmithKline
Non-randomizedSequentialOpen-labelTreatment

Summary

This study is designed to study the pharmacokinetic (PK) and safety profiles of a single dose of efimosfermin alfa in participants with varying degrees of Hepatic Impairment (HI) (assessed by Child-Pugh score) due to steatotic liver disease, with and without significant alcohol consumption.

Timeline

Start
2026-03-13
Primary completion
2027-10-13
Completion
2027-10-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Efimosfermin alfa Unknown — Subcutaneous

Indications