drugset / Trial / NCT07361562

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

NCT07361562 ↗

Phase 1 Recruiting 100 enrolled Cogent Biosciences, Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

This is an open-label, phase 1/1b study evaluating the safety, tolerability, pharmacokinetic (what the body does to the drug), pharmacodynamic (what the drug does to the body), and antitumor activity of CGT4255 in adult participants with advanced solid tumors with ERBB2 alterations or HER2 overexpression.

Timeline

Start
2025-12-30
Primary completion
2028-05
Completion
2028-11

Drugs

EvaluationDrugModalityDoseRoute
Subject CGT4255 Unknown — Oral