drugset / Trial / NCT07371468

A Study of GSK5926371 in Participants With B-cell Driven Autoimmune Rheumatic Diseases (ARD)

NCT07371468 ↗

Phase 1 Recruiting 44 enrolled GlaxoSmithKline
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a 2-part study of GSK5926371 in participants with autoimmune rheumatic diseases (ARD). In part 1, participants will receive different doses of GSK5926371 to find a suitable priming dose. In part 2, participants will receive GSK5926371 at doses based on data from part 1. The study is aimed at testing if GSK5926371 is safe, well-tolerated, how the body processes the study drug, how it works in the body, and whether it triggers any immune responses.

Timeline

Start
2026-02-10
Primary completion
2028-03-15
Completion
2028-03-15

Drugs

EvaluationDrugModalityDoseRoute
Subject GSK5926371 Protein / enzyme biologic — —