drugset / Trial / NCT07373990
Short-course Tislelizumab Combined With Chemoradiotherapy for Nasopharyngeal Carcinoma
RandomizedParallel-groupOpen-labelTreatment
Summary
This trial aim to explore whether short-course tislelizumab (3 cycles of 200 mg q3w in the induction phase and 3 cycles of 400 mg q6w in the consolidation phase) yields non-inferior event-free survival compared to long-course tislelizumab (3 cycles of 200 mg q3w in the induction phase and 5 cycles of 400 mg q6w in the consolidation phase) in patients with locoregionally advanced nasopharyngeal carcinoma.
Timeline
- Start
- 2026-01-15
- Primary completion
- 2028-04-30
- Completion
- 2030-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tislelizumab | Monoclonal antibody | 400 mg | — |
| Background | Cisplatin | Other / unclassified | 100 mg/m2 | — |
| Background | Gemcitabine | Small molecule | 1000 mg/m2 | — |