drugset / Trial / NCT07373990

Short-course Tislelizumab Combined With Chemoradiotherapy for Nasopharyngeal Carcinoma

NCT07373990

Phase 3 Not yet recruiting 418 enrolled Sun Yat-sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

This trial aim to explore whether short-course tislelizumab (3 cycles of 200 mg q3w in the induction phase and 3 cycles of 400 mg q6w in the consolidation phase) yields non-inferior event-free survival compared to long-course tislelizumab (3 cycles of 200 mg q3w in the induction phase and 5 cycles of 400 mg q6w in the consolidation phase) in patients with locoregionally advanced nasopharyngeal carcinoma.

Timeline

Start
2026-01-15
Primary completion
2028-04-30
Completion
2030-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tislelizumab Monoclonal antibody 400 mg
Background Cisplatin Other / unclassified 100 mg/m2
Background Gemcitabine Small molecule 1000 mg/m2