drugset / Trial / NCT07375290

Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors

NCT07375290

Phase 1 Recruiting 20 enrolled Children's Hospital Medical Center, Cincinnati
NaSingle-groupOpen-labelPrevention

Summary

The purpose of this pilot study is to investigate the safety and preliminarily assess efficacy of early intervention with zoledronate in high risk pediatric hematopoietic stem cell transplantation (HSCT) patients to prevent the development of bone disease and fractures and reduce potential pain and suffering.

Timeline

Start
2026-02
Primary completion
2028-01
Completion
2028-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Zoledronate Other / unclassified 0.025 mg/kg Intravenous