drugset / Trial / NCT07378644

Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease

NCT07378644 ↗

Phase 2/3 Recruiting 400 enrolled Skyhawk Therapeutics, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The goal of this clinical trial is to test if the drug SKY-0515, an oral medication, can lower harmful proteins linked to Huntington's Disease (HD) and improve the symptoms of participants with HD. This study includes men and women aged 25 and older who have HD confirmed by genetic testing and meet certain requirements for physical ability and independence.

Timeline

Start
2026-01-06
Primary completion
2028-12
Completion
2029-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator SKY-0515 Small molecule — Oral

Indications