drugset / Trial / NCT07392645

Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms

NCT07392645

Not yet recruiting 123 enrolled Lishu Gao
RandomizedParallel-groupTriple-blindTreatment

Summary

This study aims to evaluate the clinical efficacy and safety of electroacupuncture (EA) in treating Generalized Anxiety Disorder (GAD). Participants will be randomly assigned to an EA group, a sham EA group, or a waiting-list control group. All participants will continue their routine medication (Paroxetine). The primary goal is to observe the reduction in anxiety symptoms using the Hamilton Anxiety Scale (HAMA). Additionally, the study will use functional MRI (fMRI) and Magnetic Resonance Spectroscopy (MRS) to explore the brain mechanisms through which EA helps alleviate anxiety.

Timeline

Start
2026-02-01
Primary completion
2027-10-31
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Background Paroxetine Small molecule 20 mg Oral