drugset / Trial / NCT07401823

Open-Label Extension Study to Pioneer Study 6058-SCD-101

NCT07401823 ↗

Phase 2 Enrolling by invitation 50 enrolled Fulcrum Therapeutics
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label study to evaluate the safety and tolerability of long-term treatment with pociredir without a comparator in participants with SCD who have previously been treated and shown benefit with pociredir in feeder study 6058-SCD-101 (NCT05169580). Participants in this study will receive once daily doses of pociredir for up to 48 months.

Timeline

Start
2026-03-30
Primary completion
2030-02-04
Completion
2030-07-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Pociredir Small molecule — Oral

Indications