drugset / Trial / NCT07406633

KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting (SynerGIST-1st Line)

NCT07406633

Phase 2 Recruiting 46 enrolled Kumquat Biosciences Inc.
NaSequentialOpen-labelTreatment

Summary

This study will test an experimental drug called KQB198 in combination with imatinib. The goal is to determine if this combination is safe and tolerable and assess how effective the combination is at treating GIST. Imatinib has been approved by the FDA for the treatment of different types of cancer including GIST.

Timeline

Start
2026-06
Primary completion
2027-10
Completion
2028-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Imatinib Small molecule Oral
Subject KQB198 Unknown Oral