drugset / Trial / NCT07407010

BCMA/CD3 Bispecific Antibody as Bridging Therapy Before CAR-T Cell Infusion in RRMM

NCT07407010

Phase 1 Not yet recruiting 10 enrolled Institute of Hematology & Blood Diseases Hospital, China
NaSingle-groupOpen-labelTreatment

Summary

This study is a prospective, single-arm, multicenter trial designed to evaluate the hematologic response rate and safety of BCMA/CD3 bispecific antibody bridging therapy prior to CAR-T cell infusion in patients with relapsed/refractory multiple myeloma (RRMM).

Timeline

Start
2026-06-01
Primary completion
2027-05-31
Completion
2028-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject CM336 Monoclonal antibody