drugset / Trial / NCT07414836

A First-in-Human Study of BG-C0979 in Adults With Advanced Solid Tumors

NCT07414836

Phase 1 Recruiting 84 enrolled BeOne Medicines
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of BG-C0979 monotherapy or in combination with tislelizumab in participants with selected advanced solid tumors. The study will consist of Phase 1a (Dose Escalation and Safety Expansion) and Phase 1b (Dose Expansion).

Timeline

Start
2026-04-13
Primary completion
2029-04-30
Completion
2029-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject BG-C0979 Unknown Intravenous
Subject Tislelizumab Monoclonal antibody Intravenous