drugset / Trial / NCT07421518

Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT-2 Inhibitors

NCT07421518

Phase 2 Not yet recruiting 75 enrolled AdventHealth Translational Research Institute
NaSequentialOpen-labelPrevention

Summary

The purpose of this research is to see how well a special education plan using continuous ketone monitoring (DGK) works to lower the risk of a condition called diabetic ketoacidosis (DKA) in people with type 1 diabetes (T1D) taking SGLT2 inhibitors (a type of medication commonly used to treat type 2 diabetes). This special education plan is compared to a general education plan and considers the higher risk of DKA when using medicines like SGLT2 inhibitors.

Timeline

Start
2026-06
Primary completion
2030-04
Completion
2030-04

Drugs

EvaluationDrugModalityDoseRoute
Background Sotagliflozin Small molecule