drugset / Trial / NCT07423390

Study on the Efficacy and Safety of Mecobalamin in Preventing Taxane-related Peripheral Neuropathy

NCT07423390

Phase 3 Recruiting 326 enrolled Qinghai Red Cross Hospital
RandomizedParallel-groupSingle-blindPrevention

Summary

Some patients receiving taxane-based chemotherapy experience numbness, tingling, or pain in their hands and feet, known as chemotherapy-induced peripheral neuropathy (CIPN). This study aims to find out whether oral mecobalamin can prevent or reduce CIPN. Participants will be assigned to take mecobalamin or to receive no routine mecobalamin prevention during chemotherapy, and outcomes will be compared between groups.

Timeline

Start
2026-02-24
Primary completion
2029-03-30
Completion
2029-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject methylcobalamin Small molecule 0.5 mg Oral