drugset / Trial / NCT07423598

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels

NCT07423598

Phase 1 Completed 40 enrolled AstraZeneca Parexel · collab
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate pharmacodynamics (PD) of AZD0780 compared with placebo by assessment of low-density lipoprotein-cholesterol (LDL-C) levels following repeated oral dosing in healthy adults with elevated LDL-C levels.

Timeline

Start
2026-02-24
Primary completion
2026-06-29
Completion
2026-06-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Laroprovstat Small molecule Oral

Indications

No indication recorded.