A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively

Phase 3 Recruiting 400 enrolled Karuna Therapeutics, Inc.

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the long-term safety and tolerability of KarXT and KarX-EC for the treatment of Schizophrenia and autism-related irritability in adolescents, respectively

Timeline

Start: 2026-04-07
Primary completion: 2030-03-08
Completion: 2030-03-08

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Trospium	Small molecule	—	—

A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively

Summary

Timeline

Drugs

Indications