drugset / Trial / NCT07428759

Trial to Evaluate Safety and Immune Response of an Investigational Pneumococcal Vaccine in Adults Aged 50 To 64 Years

NCT07428759

Phase 1 Active not recruiting 121 enrolled GlaxoSmithKline
RandomizedParallel-groupTriple-blindPrevention

Summary

This study will evaluate the safety and immune response of a new formulation of pneumococcal vaccine, PnMAPS30plus, in healthy adults aged 50 to 64 years. Participants will receive a single dose of either the investigational vaccine or an approved pneumococcal vaccine (PCV20) and will be monitored for approximately six months. The study aims to determine if PnMAPS30plus is safe and well-tolerated and whether it helps the body produce antibodies that protect against pneumococcal disease.

Timeline

Start
2026-03-10
Primary completion
2026-12-09
Completion
2026-12-09

Drugs

EvaluationDrugModalityDoseRoute
Subject PCV20 Vaccine Intramuscular
Subject Pn-MAPS30plus Vaccine Intramuscular

Indications