drugset / Trial / NCT07433335

A Study to Assess the Safety and Tolerability of SR-878 in Patients With Rheumatoid Arthritis

NCT07433335 ↗

Phase 1 Recruiting 27 enrolled SciRhom GmbH FGK Clinical Research GmbH · collab
NaSingle-groupOpen-labelTreatment

Summary

SR-878 is a newly developed medicine that aims to treat autoimmune disorders. It inhibits a protein (iRhom2), that regulates enzymes that are involved in the production of cytokines (small proteins that are crucial in controlling the activity of immune system cells). The aim of this clinical trial is to find a suitable safe and effective SR-878 dose for patients with rheumatoid arthritis. The study will include a screening period, an inpatient treatment period, and an outpatient follow-up period. The study duration for an individual participant is up to 113 days (about 16 weeks).

Timeline

Start
2026-04-07
Primary completion
2028-02-29
Completion
2028-02-29

Drugs

EvaluationDrugModalityDoseRoute
Subject SR-878 Unknown — Intravenous

Indications