drugset / Trial / NCT07434284
Exploratory Clinical Study of cCTL in Combination With Immunotherapy for Advanced Gynecologic Malignancies
Phase 0
Recruiting
20 enrolled
Obstetrics & Gynecology Hospital of Fudan University
Nanjing University · collab
NaSingle-groupOpen-labelTreatment
Summary
This study is a single-arm, open-label, interventional, and exploratory clinical trial,the goal of which is to evaluate the safety and clinical efficacy of the novel tumor-specific cytotoxic T lymphocyte (cCTL) injection in combination with immunotherapy for the treatment of advanced gynecologic malignancies.The trial will also explore the preliminary efficacy and immunological characteristics of this therapy in a small sample of patients. 5-20 participants will be enrolled.
Timeline
- Start
- 2026-02
- Primary completion
- 2027-12
- Completion
- 2028-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | cCTL | Cell therapy | 2e+07 cells/kg | Intravenous |
| Subject | cCTL | Cell therapy | 5e+07 cells/kg | Intravenous |