drugset / Trial / NCT07434284

Exploratory Clinical Study of cCTL in Combination With Immunotherapy for Advanced Gynecologic Malignancies

NCT07434284 ↗

NaSingle-groupOpen-labelTreatment

Summary

This study is a single-arm, open-label, interventional, and exploratory clinical trial,the goal of which is to evaluate the safety and clinical efficacy of the novel tumor-specific cytotoxic T lymphocyte (cCTL) injection in combination with immunotherapy for the treatment of advanced gynecologic malignancies.The trial will also explore the preliminary efficacy and immunological characteristics of this therapy in a small sample of patients. 5-20 participants will be enrolled.

Timeline

Start
2026-02
Primary completion
2027-12
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject cCTL Cell therapy 2e+07 cells/kg Intravenous
Subject cCTL Cell therapy 5e+07 cells/kg Intravenous