drugset
drugset / Trial / NCT07434882

The Efficacy of Sesewanua (Clerodendrum Fragrans Wild) Mouthwash in Reducing Oral Bacteria Growth: A Quasi-Experimental Study in Nursing Practice

NCT07434882 ↗

Completed 100 enrolled Poltekkes Kemenkes Manado
NaSingle-groupOpen-labelTreatment

Summary

Background and Objectives: This study investigated the antibacterial efficacy of Sesewanua (Clerodendrum fragrans Wild) extract as a mouthwash alternative to mitigate oral bacteria, particularly Streptococcus mutans. Materials and Methods: A quasi-experimental design was employed with a cohort of 100 female students, divided into four groups to assess varying concentrations (1%, 2%, and 4%) of Sesewanua extract, along with a purified water control. The extraction process involved mechanical grinding followed by maceration with 70% ethanol to maximize the extraction of bioactive compounds. Microbiological analysis was conducted post-intervention to measure the reduction in bacterial counts.

Timeline

Start
2025-06-19
Primary completion
2025-11-25
Completion
2025-11-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Sesewanua extract Unknown 1 % Other
Subject Sesewanua extract Unknown 2 % Other
Subject Sesewanua extract Unknown 4 % Other

Indications

No indication recorded.