drugset / Trial / NCT07435051
Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III Osteomyelitis
Phase 3
Not yet recruiting
280 enrolled
Second Affiliated Hospital, School of Medicine, Zhejiang University
RandomizedParallel-groupTriple-blindTreatment
Summary
A Multicenter, Prospective, Randomized Controlled Trial to Evaluate the Efficacy and Safety of Bisphosphonates Combined with Vancomycin in the Treatment of Refractory Osteomyelitis
Timeline
- Start
- 2026-05-01
- Primary completion
- 2029-12-31
- Completion
- 2030-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alendronic Acid | Small molecule | 70 mg | Oral |
| Comparator | Vancomycin | Other / unclassified | 1 g | Intravenous |
| Background | Linezolid | Other / unclassified | — | Oral |