drugset / Trial / NCT07435779

Autologous CAR-T Cell Therapy for Refractory and Relapsing Ulcerative Colitis: A Single-Center Exploratory Study

NCT07435779

Phase 0 Recruiting 12 enrolled Hebei Senlang Biotechnology Inc., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

A Single-Center, Open-Label, Single-Arm Exploratory Clinical Study on the Use of Autologous CAR-T Cell Therapy Injection for the Treatment of Refractory and Relapsing Ulcerative Colitis: A Preliminary Exploration of 12-Week Clinical Remission with Autologous CAR-T Cell Injection in Refractory and Relapsing Ulcerative Colitis.

Timeline

Start
2026-02-04
Primary completion
2027-02-04
Completion
2028-02-04

Drugs

EvaluationDrugModalityDoseRoute
Subject BCMA CAR-T Cell therapy 1e+06 cells/kg Intravenous
Subject CD19 CAR-T Cell therapy 1e+06 cells/kg Intravenous
Subject CD19×BCMA Cell therapy 1e+06 cells/kg Intravenous

Indications

No indication recorded.