Mortality Control Program for Economically Productive Age Group in Tribal Area of Melghat.

Summary

Background: Age specific mortality rate (ASMR) of 16-60 years is very high in Indian tribal areas due to communicable and non-communicable diseases. Objectives: The primary objective is to reduce the ASMR in 16-60 years age group by at-least 30% from 16 tribal villages of Melghat. The secondary objectives are to reduce cause-specific mortality rates (CSMR) in 16-60 years age group because of diarrhoea, malaria, pneumonia, etc. Design: Community-based, single-centered, parallel-arm, cluster randomised controlled trial. Setting: 36 tribal villages/clusters (research phase: 2004-2015) and 44 new villages (replication phase: 2016-2022) were externally randomized by lottery method to intervention arm (IA) or control arm (CA). Participants: All persons in age group of 16-60 years from inaccessible 80 tribal villages. Interventions: Trained VHWs in IA, provided behaviour change communication, treatment and referral. Except principal investigator, other study staff and participants were double blinded.

Timeline

Start

2004-01-01

Primary completion

2015-12-31

Completion

2023-08-31

Publications

• Background Hunter DJ, Reddy KS. Noncommunicable diseases. N Engl J Med. 2013 Oct 3;369(14):1336-43. doi: 10.1056/NEJMra1109345. No abstract available.
• Background Masquelier B, Hug L, Sharrow D, You D, Mathers C, Gerland P, Alkema L; UN Inter-agency Group for Child Mortality Estimation. Global, regional, and national mortality trends in youth aged 15-24 years between 1990 and 2019: a systematic analysis. Lancet Glob Health. 2021 Apr;9(4):e409-e417. doi: 10.1016/S2214-109X(21)00023-1. Epub 2021 Mar 1.
• Background Sharma D, Kiran T, Goel K, Junaid KP, Rajagopal V, Gupta M, Kaundal H, Sharma S, Bahl A. Comprehensive assessment of age-specific mortality rate and its incremental changes using a composite measure: A sub-national analysis of rural Indian women. Front Med (Lausanne). 2022 Nov 29;9:1046072. doi: 10.3389/fmed.2022.1046072. eCollection 2022.
• Background GBD 2021 Demographics Collaborators. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021. Lancet. 2024 May 18;403(10440):1989-2056. doi: 10.1016/S0140-6736(24)00476-8. Epub 2024 Mar 11.

Drugs

Indications