drugset / Trial / NCT07439445

Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori Eradication

NCT07439445

Recruiting 70 enrolled Peking University First Hospital
NaSingle-groupOpen-labelTreatment

Summary

To investigate the efficacy, safety, and compliance of a simplified strategy using vonoprazan plus clarithromycin for first-line treatment in patients with Helicobacter pylori infection, among those infected with strains without clarithromycin resistance gene mutations based on fecal clarithromycin resistance gene detection.

Timeline

Start
2026-04-25
Primary completion
2027-02-13
Completion
2027-02-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Clarithromycin Small molecule 500 mg Oral
Subject Vonoprazan Other / unclassified 20 mg Oral