drugset / Trial / NCT07439445
Simplified Dual Regimen Guided by Fecal Clarithromycin Resistance Gene Detection for First-line H. Pylori Eradication
NaSingle-groupOpen-labelTreatment
Summary
To investigate the efficacy, safety, and compliance of a simplified strategy using vonoprazan plus clarithromycin for first-line treatment in patients with Helicobacter pylori infection, among those infected with strains without clarithromycin resistance gene mutations based on fecal clarithromycin resistance gene detection.
Timeline
- Start
- 2026-04-25
- Primary completion
- 2027-02-13
- Completion
- 2027-02-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clarithromycin | Small molecule | 500 mg | Oral |
| Subject | Vonoprazan | Other / unclassified | 20 mg | Oral |