drugset / Trial / NCT07444606

Dose Ranging, Toxicity Seeking, Phase 1 Trial of Oncolytic Adenoviral Therapy for Melanoma Intracranial and Extracranial Metastases

NCT07444606

Phase 1 Not yet recruiting 50 enrolled M.D. Anderson Cancer Center
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to find the recommended dose level and recommended number of injections of the study agent DNX-2401 that can be given to patients with metastatic melanoma that have intracranial and/or extracranial lesions.

Timeline

Start
2026-08-31
Primary completion
2027-01-30
Completion
2029-01-30

Drugs

EvaluationDrugModalityDoseRoute
Subject tasadenoturev Unknown Other

Indications