drugset / Trial / NCT07447076
Study of Novel Therapies for Young People With Recurrent/Progressive Atypical Teratoid Rhabdoid Tumor (ATRT)
Phase 2
Recruiting
29 enrolled
Sabine Mueller, MD, PhD
Pacific Pediatric Neuro-Oncology Consortium · collabRally Foundation · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This is a multi-treatment arm study that will be conducted through the Pacific Pediatric Neuro-oncology Consortium (PNOC).The study will assess the safety and efficacy of novel therapies and combinatorial strategies for participants with recurrent or progressive ATRT.
Timeline
- Start
- 2026-06-17
- Primary completion
- 2035-12-31
- Completion
- 2036-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gemcitabine | Small molecule | 1200 mg/m2 | Intravenous |
| Subject | Paxalisib | Small molecule | 15 mg/m2 | Oral |