drugset / Trial / NCT07448038

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

NCT07448038 ↗

Phase 2 Recruiting 162 enrolled Genentech, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The main purpose of the study is to evaluate the efficacy of selnoflast compared with placebo in participants with atherosclerosis, at high-risk for major adverse cardiovascular event (MACE), who are currently on standard-of-care (SOC) therapy.

Timeline

Start
2026-06-05
Primary completion
2028-01-31
Completion
2028-02-28

Drugs

EvaluationDrugModalityDoseRoute
Subject Selnoflast Small molecule — Oral

Indications