drugset / Trial / NCT07449351

Psilocybin Microdosing on Cognition, Mood and Quality of Life

NCT07449351

Phase 0 Not yet recruiting 20 enrolled Yale University Hartford HealthCare · collab
RandomizedParallel-groupDouble-blindBasic science

Summary

This study is being conducted to evaluate how of 30 days of intermittently microdosed psilocybin affects mood, cognition, subjective well-being and structural/functional MRI results compared to a placebo. Investigators hypothesize that compared to placebo, 30 days of intermittently microdosed psilocybin will produce observable changes in mood, cognition, subjective well-being and MRI, in the absence of psychedelic experiences.

Timeline

Start
2026-08-10
Primary completion
2028-04-01
Completion
2028-04-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Psilocybin Other / unclassified 2 mg

Indications

No indication recorded.