drugset / Trial / NCT07449442

SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty

NCT07449442 ↗

Recruiting 60 enrolled Poznan University of Medical Sciences
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet × neutrophil / lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether iPACK block with ACB attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.

Timeline

Start
2026-03-01
Primary completion
2026-05-31
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ropivacaine Hydrocloride Unknown 20 ml Other

Indications