drugset / Trial / NCT07449442
SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet × neutrophil / lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether iPACK block with ACB attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.
Timeline
- Start
- 2026-03-01
- Primary completion
- 2026-05-31
- Completion
- 2026-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ropivacaine Hydrocloride | Unknown | 20 ml | Other |