drugset / Trial / NCT07450378

QLC7401 in Participants With Heterozygous Familial Hypercholesterolemia (HeFH)

NCT07450378 ↗

Phase 3 Not yet recruiting 120 enrolled Qilu Pharmaceutical Co., Ltd.
RandomizedParallel-groupDouble-blindTreatment

Summary

This Phase III clinical trial aims to assess the efficacy and safety of QLC7401 Treatment in adults with Heterozygous Familial Hypercholesterolemia on a stable lipid-lowering therapy. Participants will be randomly assigned to receive subcutaneous injections of either QLC7401 or a placebo according to the study schedule.

Timeline

Start
2026-05
Primary completion
2028-04
Completion
2028-07

Drugs

EvaluationDrugModalityDoseRoute
Subject QLC7401 Small interfering RNA (siRNA) — Subcutaneous